● Jang MS, Lee SJ, Kim CJ, Lee CW, Kim E. Phosphorylation by polo-like kinase 1 incuces the tumor-suppressing activity of FADD. Oncogene 2010 advance online publication 4 October.

Kim HS, Baek KH, Ha GH, Lee JC, Kim YN, Lee J, Park HY, Lee NR, Lee Ho, Cho Y, and Lee CW. The hsSsu72 phosphatase is a cohesion-binding protein that regulates the resolution of sister chromatid arm cohesion. EMBO Journal 2010 Oct 20;29(20):3544-57. (IF 8.993)

● Kim EG, Shin HJ, Lee CG, Park HY, Cho SH, Min KU, Cho ML, Park SH, Lee CW. DNA methylation and not allelic variation regulates STAT6 expression in human T cells. Clinical and Experimental Medicine 2010 Sep;10(3):143-52.

● Oh ET, Byun MS, Lee H, Park MT, Jue DM, Lee CW, Lim BU, Park HJ. Aurora-A Contributes to Radioresistance by Increasing NF-kappaB DNA Binding. 2010 Radiationresearch 2010 Sep;174(3):265-73.

● Kim HS, Kim HS, Lee CW, ChungDH. T Cell Ig Domain and Mucin Domain 1Engagement on Invariant NKT Cells in the Presence of TCR Stimulation EnhancesIL-4 Production but Inhibits IFN-{gamma} Production. Journal of Immunology 2010 Apr 15;184(8):4095-106.


● Ha GH, Kim HS, Lee CG, Park HY, Kim EJ, Shin HJ, Lee JC, Lee KW, Lee CW. Mitotic catastrophe is the predominant response to histone acetyltransferase depletion. Cell Death and Differentiation 2009 Mar; 16(3): 483-97. (IF 8.240)

● Kim HS, Jeon YK, Ha GH, Park HY, Kim YJ, Shin HJ, Lee CG, Chung DH, Lee CW. Functional interaction between BubR1 and securin in an anaphase-promoting complex / cyclosome Cdc20 -independent manner. Cancer Research 2009 Jan 1; 69(1): 27-36. (IF 7.543)

● Lee J, Lee CG, Lee KW, Lee CW. Cross-talk between BubR1 expression and commitment to differentiate in adipose-derived mesenchymal stem cells. Experimental &Molecular Medicine 2009 Dec 31; 41 (12): 873-9.

● Shin HJ, Lee JB, Park SH, Chang J, Lee CW. T-bet expression is regulated by EGR1 mediated signaling in activated T cells. Clinical Immunology 2009 Jun; 131(3): 385-94.


● Jang MS, Sul JW, Choi BJ, Lee SJ, Suh JH, Kim NS, Kim WH, Lim DS, Lee CW, Kim E. Negative feedback regulation of Aurora-A via phosphorylation of Fas-associated factor-1. The Journal of Biological Chemistry 2008 Nov 21; 283(47): 32344-51.

● Youn JI, Park SH, Jin HT, Lee CG, Seo SH, Song MY, Lee CW, Sung YC. Enhanced delivery efficiency of recombinant adenovirus into tumor and mesenchymal stem cells by a novel PTD. Cancer Gene Therapy 2008 Nov; 15(11): 703-12.


● Ha GH, Baek KH, Kim HS, Jeong SJ, Kim CM, McKeon F, Lee CW. p53 activation in response to mitotic spindle damage requires signaling via BubR1-mediated phosphorylation. Cancer Research 2007 Aug 1; 67(15): 7155-64. (IF 7.543)

● Park HY, Jeon YK, Shin HJ, Kim IJ, Kang HC, Jeong SJ, Chung DH, Lee CW. Differential promoter methylation may be a key molecular mechanism in regulating BubR1 expression in cancer cells. Experimental &Molecular Medicine 2007 Apr 30; 39(2): 195-204.


● Baek KH, Park HY, Kang CM, Kim SJ, Jeong SJ, Hong EK, Park JW, Sung YC, Suzuki T, Kim CM, Lee CW. Overexpression of hepatitis C virus NS5A protein induces chromosome instability via mitotic cell cycle dysregulation. Journal of Molecular Biology 2006 May 26; 359(1): 22-34.

● Park JW, Park JE, Lee JA, Lee CW, Kim CM. Cyclooxygenase-2 (COX-2) is directly involved but not decisive in proliferation of human hepatocellular carcinoma cells. Journal of Cancer Research and Clinical Oncology 2006 Mar; 132(3): 184-92.


● Shin HJ, Park HY, Jeong SJ, Park HW, Kim YK, Cho SH, Kim YY, Cho ML, Kim HY, Min KU, Lee CW. STAT4 expression in human T cells is regulated by DNA methylation but not by promoter polymorphism. Journal of Immunology 2005 Dec 1; 175(11): 7143-50.

● Baek KH, Shin HJ, Jeong SJ, Park JW, McKeon F, Lee CW, Kim CM. Caspases-dependent cleavage of mitotic checkpoint proteins in response to microtubule inhibitor. Oncology research 2005; 15(3): 161-8. (Corresponding author)


● Jeong SJ, Shin HJ, Kim SJ, Ha GH, Cho BI, Baek KH, Kim CM, Lee CW. Transcriptional abnormality of the hsMAD2 mitotic checkpoint gene is a potential link to hepatocellular carcinogenesis. Cancer Research 2004 Dec 1; 64(23): 8666-73. (IF 7.543)

● Yoon YM, Baek KH, Jeong SJ, Shin HJ, Ha GH, Jeon AH, Hwang SG, Chun JS, Lee CW. WD repeat-containing mitotic checkpoint proteins act as transcriptional repressors during interphase. FEBS Letters 2004 Sep 24; 575(1-3): 23-9.

● Shin HJ &Lee CW. et al. 2004. Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability. Nature Reviews Cancer 4: 91. (Highlights).


● Shin HJ, Baek KH, Jeon AH, Chung DH, Lee SJ, Lee HS, Sung YC, McKeon F, and Lee CW. Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability. Cancer Cell (Cell press) 2003. 4: 483-497. (IF 25.288)

● ShinHJ, Baek KH, Jeon AH, Kim SJ, Jang KL, Sung YC, Kim CM, Lee CW. Inhibitionof histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation. Oncogene 2003 Jun19; 22(25): 3853-8.

● Baek KH, Shin HJ, Yoo JK, Cho JH, Choi YH, Sung YC, McKeonF, Lee CW. p53 deficiency anddefective mitotic checkpoint in proliferating T lymphocytes increase chromosomal instability through aberrant exit from mitotic arrest. Journal of Leukocyte Biology 2003Jun; 73(6): 850-61.

~ 2002

● Ahn JY, Jung EY, Kwun HJ, Lee CW, Sung YC, Jang KL. Dual effects of hepatitis B virus X protein on the regulation of cell-cycle control depending on the status of cellular p53. The Journal of General Virology 2002 Nov; 83(Pt 11): 2765-72.

● Yang SH, Lee CG, Lee CW, Choi EJ, Yoon SK, Ahn KS, Sung YC. Hepatitis C virus core inhibits the Fas-mediated p38 mitogen activated kinase signaling pathway in hepatocytes. Molecules and Cells 2002 Jun 30; 13(3): 452-62.

● Choi YH, Rho WS, Kim ND, Prak SJ, Shin DH, Kim JW, Im SH, Won HS, Lee CW, Chae CB, Sung YC. Short peptides with induced beta-turn inhibit the interaction between HIV-1 gp120 and CD4. Journal of medicinal chemistry 2001 Apr 26; 44(9): 1356-63.

● Lee CH, Choi YH, Yang SH, Lee CW, Ha SJ, Sung YC. Hepatitis C virus core protein inhibits interleukin 12 and nitric oxide production from activated macrophages. Virology 2001 Jan 5; 279(1): 271-9.

● Shikama N, Chan HM, Krstic-Demonacos M, Smith L, Lee CW, Cairns W, La Thangue NB. Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators. Molecular and Cellular Biology 2000 Dec; 20(23): 8933-43.

Lee CW*, Shikama N*, France S, Delavaine L, Lyon J, Krstic-Demonacos M, and La Thangue NB. A new co-factor for p300/CBP that regulates the p53 response. Molecular Cell (Cell press) 1999 4: 365-376. (IF 14.608)

Lee CW, La Thangue NB. Promoter specificity and stability control of the p53-related protein p73. Oncogene 1999 Jul 22; 18(29): 4171-81.

Lee CW, Sørensen TS, Shikama N, La Thangue NB. Functional interplay between p53 and E2F through co-activator p300. Oncogene 1998 May 28; 16(21): 2695-710.

● de la Luna S, Burden MJ, Lee CW, La Thangue NB. Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal. Journal of Cell Science 1996 Oct; 109 ( Pt 10): 2443-52.

● Sørensen TS, Girling R, Lee CW, Gannon J, Bandara LR, La Thangue NB. Functional interaction between DP-1 and p53. Molecular and Cellular Biology 1996 Oct; 16(10): 5888-95.

Lee CW, Chang J, Lee KJ, Sung YC. The Bel1 protein of human foamy virus contains one positive and two negative control regions which regulate a distinct activation domain of 30 amino acids. Journal of Virology 1994 Apr; 68(4): 2708-19.

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Sungkyunkwan University School of Medicine, Suwon 440-746, Korea

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